产品货号：
Z12041
中文名称：
BRE抗体
英文名称：
Anti-BRE Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BRE Antibody |
| 指标别名 | BABAM2,BRCA1 A complex subunit BRE,BRCC4,BRCC45,BRE,BRISC and BRCA1-A complex member 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | BRE |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | BRCC45 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human BRCC45.The immunogen is located within the last 50 amino acids of BRCC45. |
| 计算分子量 | 44kDa |
| 成分 | BRCC45 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | BRCC45 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs.Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36.This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage.BRCC45 has also been suggested to function as a death receptor-associated anti-apoptotic protein by inhibiting the BID-induced activation of the mitochondrial apoptotic pathway.Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas,suggesting that BRCC45 may promote tumorigenesis when overexpressed.At least three isoforms of BRCC45 are known to exist. |
| Uniprot ID | Q9NXR7 |
| 基因名全称 | Brain and reproductive organ-expressed (TNFRSF1A modulator) |
| 蛋白名全称 | Brain and reproductive organ-expressed (TNFRSF1A modulator) |
| 推荐稀释比 | BRCC45 antibody can be used for detection of BRCC45 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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